Lupoid sclerosis: a possible pathogenetic role for antiphospholipid antibodies.
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چکیده
منابع مشابه
Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms.
L UPUS ANTICOAGULANTS (LA), anticardiolipin (aCLj antibodies, the antiphospholipid (aPL) syndrome, and the associated predisposition to thrombosis pose many difficulties ranging from practical issues of detection and patient management to conceptual issues regarding the mechanism(sj underlying the associated thrombotic tend e n ~ y . " ~ aPL antibodies represent a family of Igs with reactivity ...
متن کاملAntiphospholipid antibodies.
Antiphospholipid antibodies (APLAs) are proteins that may be present in the blood and may increase your risk for blood clots or pregnancy losses. If you have a history of blood clots or recurrent pregnancy losses, you may have been tested for the presence of APLAs in your blood. The purpose of this Cardiology Patient Page is to provide information for persons with APLAs about the disorder and a...
متن کاملActivation of endothelial cells by antiphospholipid antibodies--a possible mechanism triggering thrombosis in patients with antiphospholipid syndrome.
Antiphospholipid syndrome (APS) is an antibody-mediated hypercoagulable state characterized by recurrent venous and arterial thromboembolic events. The presence of serum antibodies are collectively termed as antiphospholipid antibodies (aPL) and is the hallmark of the disease. Interest in the pathogenesis has mostly been focused on the blood coagulation factor. However, endothelial cells might ...
متن کاملAntiphospholipid antibodies and stroke.
The clinical study of stroke is a recent occurrence. The clarion call awakening interest consisted of two reports that appeared during the years following World War II : the detailed description by Kubik and Adams [1) of the clinical and pathologic findings in patients with basilar artery occlusion, and C. Miller Fisher's monograph [2] directing attention to the signs and symptoms found in pati...
متن کاملAntiphospholipid antibodies and infections.
Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as "autoimmune" and "infectious" types. This distinction, however, has subsequently been found not to be absolute.
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1985
ISSN: 0003-4967
DOI: 10.1136/ard.44.4.281